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Anita B Roberts Selected Research

Transforming Growth Factor beta (TGF-beta)

3/2010Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer.
7/2008Absence of Smad3 induces neutrophil migration after cutaneous irradiation: possible contribution to subsequent radioprotection.
10/2007Absence of Smad3 confers radioprotection through modulation of ERK-MAPK in primary dermal fibroblasts.
9/2007Lentiviral reporter constructs for fluorescence tracking of the temporospatial pattern of Smad3 signaling.
6/2006Smad3 deficiency alters key structural elements of the extracellular matrix and mechanotransduction of wound closure.
2/2006Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.
1/2006Smad4-expression is decreased in breast cancer tissues: a retrospective study.
5/2005Breast cancer cells induce stromal fibroblasts to express MMP-9 via secretion of TNF-alpha and TGF-beta.
5/2005Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali.
4/2005Selective reduction of fibrotic markers in repairing corneas of mice deficient in Smad3.
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Anita B Roberts Research Topics

Disease

13Neoplasms (Cancer)
01/2016 - 02/2002
10Wounds and Injuries (Trauma)
09/2008 - 03/2002
9Fibrosis (Cirrhosis)
10/2007 - 05/2003
6Breast Neoplasms (Breast Cancer)
03/2010 - 12/2003
5Inflammation (Inflammations)
07/2008 - 03/2002
5Carcinogenesis
02/2006 - 02/2002
3Neoplasm Metastasis (Metastasis)
02/2006 - 07/2004
3Radiation Fibrosis Syndrome (Radiation Fibrosis)
04/2004 - 03/2002
2Leukemia
08/2004 - 01/2003
2Cicatrix (Scar)
03/2004 - 12/2003
1Burns
05/2005
1Corneal Injuries
05/2005
1Retinal Detachment (Retinal Detachments)
10/2004
1Proliferative Vitreoretinopathy
10/2004
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
08/2004
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2004
1Pulmonary Fibrosis (Fibrosing Alveolitis)
08/2004
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
04/2004
1Radiation Injuries (Radiation Sickness)
04/2004
1Ureteral Obstruction
11/2003
1Albuminuria
06/2003
1Lung Diseases (Lung Disease)
03/2003

Drug/Important Bio-Agent (IBA)

26Transforming Growth Factor beta (TGF-beta)IBA
03/2010 - 02/2002
3Transforming Growth Factors (Transforming Growth Factor)IBA
01/2016 - 12/2003
3Transforming Growth Factor beta1 (TGF beta 1)IBA
03/2010 - 08/2004
3CytokinesIBA
09/2008 - 09/2004
3Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
01/2006 - 01/2003
2LysophospholipidsIBA
11/2004 - 09/2004
2Messenger RNA (mRNA)IBA
08/2004 - 12/2003
2Proteins (Proteins, Gene)FDA Link
08/2004 - 01/2003
1Conditioned Culture MediaIBA
03/2010
1PlacebosIBA
09/2008
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2008
1Green Fluorescent ProteinsIBA
09/2007
1Red Fluorescent ProteinIBA
09/2007
1ElementsIBA
09/2007
1Bone Morphogenetic Protein 7IBA
08/2007
1Estrogen ReceptorsIBA
01/2006
1Formaldehyde (Formol)FDA Link
01/2006
1ParaffinIBA
01/2006
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
05/2005
1Neutralizing AntibodiesIBA
05/2005
1Epidermal Growth Factor (EGF)IBA
05/2005
1LigandsIBA
05/2005
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2005
1Activins (Activin)IBA
05/2005
1AlkaliesIBA
05/2005
1N-acetyltalosaminuronic acid (NAT)IBA
04/2005
1Fibronectins (Fibronectin)IBA
04/2005
1Transforming Growth Factor beta2IBA
04/2005
1Protein Isoforms (Isoforms)IBA
04/2005
1p38 Mitogen-Activated Protein KinasesIBA
01/2005
1Biological ProductsIBA
11/2004
1ThrombinFDA Link
11/2004
1lysophosphatidic acidIBA
11/2004
1PPAR-betaIBA
10/2004
1Activin Receptors (Activin Receptor)IBA
10/2004
1Retinal Pigments (Pigments, Visual)IBA
10/2004
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
09/2004
1Smad3 ProteinIBA
08/2004
1Transforming Growth Factor-beta Type I ReceptorIBA
07/2004
1Phosphotransferases (Kinase)IBA
07/2004
1halofuginoneIBA
04/2004
1Capsules (Microcapsules)IBA
02/2004
1C.I. direct red 80IBA
12/2003
1Connective Tissue Growth FactorIBA
12/2003
1CollagenIBA
11/2003
1AlbuminsIBA
06/2003
1SmokeIBA
03/2003
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2003

Therapy/Procedure

1Therapeutics
03/2010
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
07/2008
1Skin Transplantation (Skin Grafting)
07/2008
1Radiotherapy
04/2004
1Cataract Extraction
02/2004